Sažetak
Objective: To investigate the effects of different anesthesia methods on the levels of inflammatory and coagulation factors in the peripheral blood of elderly patients undergoing hip surgery.
Methods: 144 elderly patients undergoing hip arthroplasty in our hospital were randomly divided into ultrasound-guided lumbar-sciatic nerve block (group A) and epidural anesthesia (group B), 72 cases in each group. The postoperative hemodynamic indexes, pain score, inflammatory factors and coagulation factor levels were compared between the two groups.
Results: (1) The postoperative VAS score of group B patients was lower than that of group A (P<0.05); (2) The SBP and DBP of group B were higher than those of group A at T1 and T2. (both P<0.05); (3) Compared with group A, the levels of IL-6, IL-8 and TNF-α in the peripheral blood of patients in group B decreased at postoperative T2, T3 and T4 (P<0.05); (4) Compared with group A, plasma FV:C, FVIII:C and FIB in group B decreased, and TT increased during surgery after T2, T3 and T4, (all P<0.05).
Conclusion: Compared with epidural anesthesia, lumbar-sciatic nerve block can reduce the levels of peripheral blood coagulation factors and inflammatory factors after surgery.
Ključne reči
Array
Array
Array
Reference
The published articles will be distributed under the Creative Commons Attribution 4.0 International License (CC BY). It is allowed to copy and redistribute the material in any medium or format, and remix, transform, and build upon it for any purpose, even commercially, as long as appropriate credit is given to the original author(s), a link to the license is provided and it is indicated if changes were made. Users are required to provide full bibliographic description of the original publication (authors, article title, journal title, volume, issue, pages), as well as its DOI code. In electronic publishing, users are also required to link the content with both the original article published in Journal of Medical Biochemistry and the licence used.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.