Abstract
Summary
Aim. Previous research has shown that CRP levels are elevated in people with metabolic syndrome (MS) and that low-intensity inflammation is characteristic of MS. The aim was to examine the level and significance of serum CRP in individuals with MS.
Methods. The study included 149 outpatients, 67 with MS (68.9 ± 8.7) and 82 without MS (68.9 ± 8.6) as controls (p> 0.05). CRP was determined by turbidimetry with normal values up to 5.0 mg / L.
Results. The average CRP level of subjects with MS was 5.33 ± 3.6 mg / L, and without MS 2.46 ± 2.03 mg / L (p <0.001). There was no significant difference in CRP concentrations between men (6.02 ± 4.88 mg / L) and women with MS (4.97 ± 2.87 mg / L) (p> 0.05). CRP levels higher than 5.0 mg / L were present in 29.8% subjects with MS and 6.1% without MS (p <0.01).
Conclusion. A significantly higher frequency of elevated values and levels of serum CRP in people with MS, compared to those without MS, indicates the importance of inflammation in the pathogenesis of MS and CRP as biomarkers and mediators of chronic inflammation.
Key words: metabolic syndrome, C-reactive protein