Sažetak
Uvod/Cilj. Oštećenje vida uzrokovano glaukomom ima snažan negativan uticaj na mentalno i fizičko zdravlje. Cilj studije bio je da se ispita uticaj primarnog glaukoma otvorenog ugla (PGOU), primarnog glaukoma zatvorenog ugla (PGZU) i pseudoeksfolijativnog glaukoma (PEG) na kvalitet života (KŽ) bolesnika u centralnoj Srbiji. Metode. U ovoj studiji preseka bila su uključena 102 bolesnika koji su lečeni zbog PGOU, PGZU ili PEG. Bolesnici su bili podeljeni u tri grupe (PGOU, PGZU i PEG) u zavisnosti od tipa glaukoma i posmatrani su šest meseci. Podaci o KŽ učesnika prikupljeni su korišćenjem upitnika National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25). Korišćenjem odgovarajućeg algoritma izračunat je ukupan rezultat iz upitnika NEI VFQ-25 za svaku grupu. Rezultati. Parametri funkcije vida bili su statistički značajno niži u PEG grupi u poređenju sa ostalim ispitivanim grupama (PEG: 61,1 ± 12,6; PGOU: 71,6 ± 17,9; PGZU: 75,7 ± 11,6), p < 0,001. Opšte zdravlje, bol u očima, vid na daljinu, socijalno funkcionisanje, periferni vid, smanjena sposobnost u svakodnevnim aktivnostima i zavisnost od drugih, takođe su bili statistički značajno niži u PEG grupi. Najbolja oštrina vida na blizinu izmerena je u PGOU grupi (76,2 ± 21,2). Najviša srednja vrednost glaukomnog ispada vidnog polja zabeležena je u PEG grupi bolesnika (14,5 ± 3,6 dB). Zaključak. Istraživanje je pokazalo da su bolesnici sa PEG imali statistički značajno lošiji KŽ u poređenju sa bolesnicima koji su bolovali od PGOU i PGZU. Najniži skor po pojedinim oblastima ispitivanja po upitniku NEI VFQ-25 bio je kod bolesnika sa PEG, kada je u pitanju bilo opšte zdravlje bolesnika, osećaj bola u očima, vid na daljinu, kao i u domenu socijalnog i svakodnevnog funkcionisanja. Dobijeni rezultati ukazuju da treba preduzeti ozbiljne mere za popravljanje kvaliteta života bolesnika sa glaukomom.
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Reference
Zhou H, Shen Z. The definition of glaucoma. In: Zhou H, Shen Z, editors. Intraocular pressure and Glaucoma. Wuhan, Chi-na: Hubei Science & Technology Press; 2010. p. 8–11.
Liu SA, Zhao ZN, Sun NN, Han Y, Chen J, Fan ZG. Transi-tions of the understanding and definition of primary glauco-ma. Chin Med J (Engl) 2018; 131(23): 2852‒9.
Choudhari N, Pathak-Ray V, Kaushik S, Vyas P, George R. Prev-alent practice patterns in glaucoma: Poll of Indian ophthal-mologists at a national conference. Indian J Ophthalmol 2016; 64(10): 715–21.
Kalayci M, Cetinkaya E, Erol MK. Prevalence of primary open-angle glaucoma in a Somalia population. Int Ophthalmol 2021; 41(2): 581‒6.
Lee JY, Akiyama G, Saraswathy S, Xie X, Pan X, Hong YK, et al. Aqueous humour outflow imaging: seeing is believing. Eye (Lond) 2021; 35(1): 202‒15.
Camp DA, Yadav P, Dalvin LA, Shields CL. Glaucoma second-ary to intraocular tumors: mechanisms and management. Curr Opin Ophthalmol 2019; 30(2): 71‒81.
Mocan MC, Mehta AA, Aref AA. Update in genetics and surgi-cal management of primary congenital glaucoma. Turk J Oph-thalmol 2019; 49(6): 347‒55.
Zhang N, Wang J, Chen B, Li Y, Jiang B. Prevalence of primary angle closure glaucoma in the last 20 years: A meta-analysis and systematic review. Front Med (Lausanne) 2021; 7: 624179.
Flores-Sánchez BC, Tatham AJ. Acute angle closure glaucoma. Br J Hosp Med (Lond) 2019; 80(12): C174‒9.
Hagiwara Y, Koh JEW, Tan JH, Bhandary SV, Laude A, Ciaccio EJ, et al. Computer-aided diagnosis of glaucoma using fundus images: A review. Comput Methods Programs Biomed 2018; 165: 1‒12.
Storgaard L, Tran TL, Freiberg JC, Hauser AS, Kolko M. Glau-coma clinical research: Trends in treatment strategies and drug development. Front Med (Lausanne) 2021; 8: 733080.
Mangione CM, Lee PP, Gutierrez PR, Spritzer K, Berry S, Hays RD, et al. Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol 2001; 119(7): 1050‒8.
Kovač B, Vukosavljević M, Djokić Kovač J, Resan M, Trajković G, Janković J, et al. Validation and cross-cultural adaptation of the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) in Serbian patients. Health Qual Life Outcomes 2015; 13: 142.
European Glaucoma Society. Optic nerve head and retinal nerve fibre layer. In: Terminology and guidelines for glaucoma. 5th ed. Br J Ophthalmol 2021; 105(Suppl 1): 71‒81.
Hodapp E, Parrish RK, Anderson DR. Clinical decisions in glau-coma. St. Louis: Mosby; 1993. 204 p.
Machado LF, Kawamuro M, Portela RC, Fares NT, Bergamo V, Souza LM, et al. Factors associated with vision-related quality of life in Brazilian patients with glaucoma. Arq Brass Oftalmol 2019; 82(6): 463‒70.
Ribeiro MV, Hasten-Reiter Júnior HN, Ribeiro EA, Jucá MJ, Bar-bosa FT, Sousa-Rodrigues CF. Association between visual im-pairment and depression in the elderly: a systematic review. Arq Bras Oftalmol 2015; 78(3): 197–201.
Courtney-Long EA, Carroll DD, Zhang QC, Stevens AC, Griffin-Blake S, Armour BS, et al. Prevalence of Disability and Disa-bility Type Among Adults--United States, 2013. MMWR Morb Mortal Wkly Rep 2015; 64(29): 777–83.
Biggerstaff KS, Lin A. Glaucoma and Quality of Life. Int Oph-thalmol Clin 2018; 58(3): 11‒22.
Shin DY, Jung KI, Park HY, Park CK. The effect of anxiety and depression on progression of glaucoma. Sci Rep 2021; 11(1): 1769.
Tharmathurai S, Muhammad-Ikmal MK, Razak AA, Che-Hamzah J, Azhany Y, Fazilawati Q, et al. Depression and Severity of Glaucoma Among Older Adults in Urban and Suburban Are-as. J Glaucoma 2021; 30(5): e205‒12.
Hirneiss C, Kortüm K. Quality of Life in Patients with Glauco-ma. Klin Monbl Augenheilkd 2016; 233(2): 148‒53. (Ger-man)
Stein JD, Khawaja AP, Weizer JS. Glaucoma in Adults-Screening, Diagnosis, and Management: A Review. JAMA 2021; 325(2): 164‒74.
Tanito M, Matsuoka Y. Proportion of Glaucoma Types and Surgeries Among Young, Pre-Old, Old, and Oldest-Old Age Groups or Different Sex Groups. Clin Ophthalmol 2022; 16: 1815‒9.
Tekin K, Inanc M, Elgin U. Monitoring and management of the patient with pseudoexfoliation syndrome: current perspec-tives. Clin Ophthalmol 2019; 13: 453–64.
McKean-Cowdin R, Varma R, Wu J, Hays RD, Azen SP; Los An-geles Latino Eye Study Group. Severity of visual field loss and health-related quality of life. Am J Ophthalmol 2007; 143(6): 1013–23.
Wolfram C, Lorenz K, Breitscheidel L, Verboven Y, Pfeiffer N. Health- and vision-related quality of life in patients with ocu-lar hypertension or primary open-angle glaucoma. Ophthalmo-logica 2013; 229(4): 227–34.
Šarenac-Vulović T, Pavlović S, Janicijević K, Todorović D, Paunović S, Petrović N, et al. Tear film stability in patients with pseudoex-foliation. Ser J Exp Clin Res 2018; 19(3): 243‒6.
Zhang X, Vadoothker S, Munir WM, Saeedi O. Ocular Surface Disease and Glaucoma Medications: A Clinical Approach. Eye Contact Lens 2019; 45(1): 11‒8.
Todorović D, Šarenac-Vulovic T, Jovanović S, Janićijević-Petrović M, Petrović N, Kontić M, et al. The impact of pseudoexfoliation and artificial tear application on the tear film stability in a pseudo-phakic eye. Srp Arh Celok Lek 2018; 146(7¬¬¬¬-8): 422‒7.
Dermenoudi M, Matsou A, Keskini C, Anastasopoulos E. Ocular Surface Disease Signs and Symptoms in Patients with Pseudo-exfoliative Glaucoma: A Case-Control Study. Vision (Basel) 2022; 6(1): 11.
Rao A, Raj N, Pradhan A, Senthil S, Garudadri CS, Verma PVKS, et al. Visual impairment in pseudoexfoliation from four tertiary centres in India. PLoS One 2020; 15(5): e0233268.
Singh VM, Yerramneni R, Madia T, Prashanthi S, Vaddavalli PK, Reddy JC. Complications and visual outcomes of cataract sur-gery in patients with pseudoexfoliation. Int Ophthalmol 2021; 41(7): 2303‒14.
Cho YK, Huang W, Nishimura E. Myopic refractive shift repre-sents dense nuclear sclerosis and thin lens in lenticular myopia. Clin Exp Optom 2013; 96(5): 479‒85.
Montana CL, Bhorade AM. Glaucoma and quality of life: fall and driving risk. Curr Opin Ophthalmol 2018; 29(2): 135‒40.
Jin S, Trope GE, Buys YM, Badley EM, Thavorn K, Yan P, et al. Reduced social participation among seniors with self-reported visual impairment and glaucoma. PLoS One 2019; 14(7): e0218540.
E JY, Schrack JA, Mihailovic A, Wanigatunga AA, West SK, Friedman DS, et al. Patterns of Daily Physical Activity across the Spectrum of Visual Field Damage in Glaucoma Patients. Ophthalmology 2021; 128(1): 70‒7.
Mabuchi F, Yoshimura K, Kashiwagi K, Shioe K, Yamagata Z, Kanba S, et al. High prevalence of anxiety and depression in patients with primary open-angle glaucoma. J Glaucoma 2008; 17(7): 552–7.
Tastan S, Iyigun E, Bayer A, Acikel C. Anxiety, depression, and quality of life in Turkish patients with glaucoma. Psychol Rep 2010; 106(2): 343–57.
Zhou C, Qian S, Wu P, Qiu C. Anxiety and depression in Chi-nese patients with glaucoma: sociodemographic, clinical, and self-reported correlates. J Psychosom Res 2013; 75(1): 72–82.
Zhang X, Olson DJ, Le P, Lin FC, Fleischman D, Davis RM. The association between glaucoma, anxiety, and depression in a large population. Am J Ophthalmol 2017; 183: 37–41.
Nelson P, Aspinall P, Papasouliotis O, Worton B, O'Brien C. Qual-ity of life in glaucoma and its relationship with visual func-tion. J Glaucoma 2003; 12(2): 139‒50.
Skalicky SE, Fenwick E, Martin KR, Crowston J, Goldberg I, McCluskey P. Impact of age-related macular degeneration in patients with glaucoma: understanding the patients' perspec-tive. Clin Exp Ophthalmol 2016; 44(5): 377‒87.
Wilson MR, Coleman AL, Yu F, Sasaki I, Bing EG, Kim MH. Depression in patients with glaucoma as measured by self-report surveys. Ophthalmology 2002; 109(5): 1018‒22.
Onakoya AO, Mbadugha CA, Aribaba OT, Ibidapo OO. Quality of life of primary open angle glaucoma patients in lagos, Nige-ria: clinical and sociodemographic correlates. J Glaucoma 2012; 21(5): 287–95.
Marčeta E, Todorovic D. The effect of glaucoma on the quality of patient’s life. Ser J Exp Clin Res 2021. doi: 10.2478/sjecr-2020-0046.