Sažetak
Uvod. Primarni mukozni melanom nosnosinusnog regiona je retka neoplazma i čini svega 1% svih melanoma. Biološko ponašanje melanoma karakteriše agresivan i nepredvidiv rast, česti lokalni recidivi, lokalne i udaljene metastaze. Prikaz bolesnika. Rad sumira rezultate prethodnih studija mukoznog melanoma nosnosinusne sluznice, a kroz prikaz dva bolesnika opisane su kliničke i patohistološke karakteristike ove retke neoplazme i naša iskustva sa dijagnostičkim i terapijskim postupcima. Zaključak. Naši rezultati pokazuju da patohistološke i imunohistohemijske analize doprinose postavljanju rane i tačne dijagnoze ovog oboljenja.
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