Scindeks Asistent Scindeks Asistent — sistem za ozbiljne časopise i one koji to žele da postanu
Vol. 74 Br. 4 (2017)
Vol. 74 Br. 4 (2017)

Unicentrična forma Kastlemanove bolesti lokalizovane u stomaku

DOI: 10.2298/VSP150915045M
Boško Milev
Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Borka Milev
Clinic for General and Thoracic Surgery, Kragujevac, Clinical Center Kragujevac, Serbia
Zoran Kostić
Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Darko Mirković
Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Nenad Perišić
Clinics for Gastroenterology and Hepathology, Military Medical Academy, Belgrade, Serbia
Olga Tasić
Institute of Pathology and Forensic Medicine, Military Medical Academy, Belgrade, Serbia
Marija Elez
Clinic for Hematology, Military Medical Academy, Belgrade, Serbia
Aleksandar Radunović
Clinic for Orthopedic Surgery, Military Medical Academy, Belgrade, Serbia
Milan Jovanović
Clinics for General Surgery, Military Medical Academy, Belgrade
Predrag Marić
Clinic for Urology, Military Medical Academy, Belgrade, Serbia
Sanja Daišević
Department of Anatomy and Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac
Rade Perelević
Clinic for Urology, Military Medical Academy, Belgrade, Serbia
Maja Vulović
Department of Anatomy and Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia

Sažetak

Uvod. Kastlemanova bolest je retko oboljenje nepoznate etiologije koje se javlja u dve kliničke forme: unicentrična ili multicentrična. Odlikuje se hiperplazijom limfnih žlezda. U literaturi se opisuju četiri patohistološka oblika: hijalinovaskularni tip, plazmocitni tip, mešoviti tip i skorije prepoznat plazmablastični tip. Promene su najčešće lokalizovane u medijastinumu, dok se abdominalna lokalizacija znatno ređe javlja, što je i bio razlog za ovaj prikaz slučaja. Prikaz bolesnika. Kod muškarca, starog 41 godinu, na magnetnoj rezonantnoj (MR) enterografiji uočena je promena u ileocekalnoj regiji bez prisustva subjektivnih simptoma iz digestivnog trakta kao i bez gubitka telesne mase. Zbog sumnje na stromalni tumor, indikovana je hirurška intervencija. Patohistološki nalaz je pokazao Kastlemanovu lymphadenopathia reactiva mesenterii (plazma-ćelijski tip) u unicentričnoj formi. Od laboratorijskih analiza jedino su bile prisutne anemija i ubrzana sedimentacija eritrocita. Zaključak. Abdominalna lokalizacija unicentrične plazmocitne forme Kastlemanove bolesti javlja se retko, a hirurška metoda lečenja predstavlja zlatni standard što je potvrđeno ovim prikazom.

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DOI: 10.2298/VSP150915045M

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